FIG. 7.

CPB-induced histologic damage in the rabbit small intestine. Intestinal loops constructed in the duodenum (top row), jejunum (middle row), or ileum (bottom row) were treated with Ringer's solution containing 20 μg of purified CPB and TI (CPB), Ringer's solution with TI (control) or Ringer's solution with 20 μg of purified CPB but no TI (CPB/NTI). After 6 h, duodenal, jejunal, or ileal loops treated with purified CPB and TI (CPB) showed severe damage (see Table 1 for details), but loops treated with TI but no CPB (control) or with purified CPB but no TI (CPB/NTI) showed normal, full-length intestinal villi with a well-preserved epithelium and lamina propria. Intestinal tissues were processed by histology using a hematoxylin and eosin stain. Sections of treated or control tissues were then photomicrographed at 200× final magnification. Representative photomicrographs of six repetitions for each condition are shown.