. 2008 Jul 14;76(10):4396–4404. doi: 10.1128/IAI.00547-08

TABLE 2.

Rabbit loop pathology in time-course experiments

Site and incubation time in min (CPB 10 μg)	Rabbit loop pathology (mean degree of damage ± SD)^a
Site and incubation time in min (CPB 10 μg)	Desquamation of epithelium	Necrosis of epithelium	Necrosis of lamina propria	Inflammation	Edema	Villous blunting	Overall severity
Duodenum
15	1.4 ± 0.1^a	1.4 ± 0.1^a	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.3 ± 0.1
30	1.5 ± 0.3^a	1.5 ± 0.3^a	1.0 ± 0.0	1.0 ± 0.0	1.3 ± 0.3	1.0 ± 0.0	1.4 ± 0.1^a
60	1.8 ± 0.3^a	1.8 ± 0.3^a	1.2 ± 0.4	1.0 ± 0.0	1.3 ± 0.3	1.0 ± 0.0	1.6 ± 0.2^a
Control	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0
Jejunum
15	2.0 ± 0.5^a	2.0 ± 0.5^a	1.5 ± 0.5^a	1.5 ± 0.5	1.5 ± 0.5	1.5 ± 0.5	1.9 ± 0.7^a
30	2.5 ± 0.3^a	2.5 ± 0.3^a	1.8 ± 0.3^a	1.5 ± 0.5	1.8 ± 0.3^a	2.3 ± 0.3^a	2.5 ± 0.3^a
60	2.8 ± 0.6^a	2.8 ± 0.6^a	2.2 ± 0.7^a	1.8 ± 1.0	1.8 ± 0.3^a	2.3 ± 0.3^a	2.8 ± 0.6^a
Control	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0
Ileum
15	1.6 ± 0.2^a	1.6 ± 0.2^a	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.5 ± 0.3^a
30	2.3 ± 0.3^a	2.3 ± 0.3^a	1.8 ± 0.3^a	1.5 ± 0.5	1.8 ± 0.3^a	2.3 ± 0.3^a	2.3 ± 0.3^a
60	2.8 ± 0.5^a	2.8 ± 0.5^a	2.0 ± 0.5^a	1.8 ± 0.8	2.1 ± 0.7^a	2.8 ± 0.3^a	2.8 ± 0.5^a
Control	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0	1.0 ± 0.0

A superscript “A” indicates a statistically significant difference (P < 0.05) relative to the control loop using the Friedman test.