FIG. 3.
Prophylactic administration of MAb F429 18 h prior to infection reduces bacterial levels and pathology. Both extracellular and internalized CFU per eye and corneal pathology were reduced after challenge with either invasive strain 6294 or cytotoxic strain 6077. Points indicate values for an individual mouse, bars indicate medians, and P values were calculated by the Mann-Whitney U test. Infectious inocula in a 5-μl volume for both strains: strain 6294, 106 CFU/eye; and strain 6077, 9.0 × 105 CFU/eye.