TABLE 2.
Localization and functional classification of σ32 regulon productsa
| Location or functional category (no. of products) | Regulon products |
|---|---|
| Location | |
| Periplasm (8) | CreAc, DsbCc, YceIc, YciMb, YehRe, YehZe, YgcIe, YibGe |
| Inner membrane (27) | CreCc, CutEc, CycAb, FtsHd, FxsAb,c,e, GntYc, HflXd, HflKd, HflCd, HtpXd, LipBc, LspAc, MacBb, MenAd, PgpAc, PhoQc, SdaCe, YafUe, YbeXc, YbeZb,c,e, YceJc, YcjFb,c, YciSb,c,e, YdgRe, YghJe, YiaAe, YtfLe |
| Cytoplasm (88) | ClpBd, ClpPd, ClpXd, CreBc, Crre, DnaJd, DnaKd, FkpBc, FimBe, FolPd, GapAd, GlnSc,e, GntXc,e, GroELSd, GrpEd, HepAc,e, Hfqc, HolCc,e, Hsp33c, HslUd, HslVd, HtpGd, IbpAd, IbpBd, IleSc,e, IspHc, LdhAb,e, Lond, MiaAd, Mfdb,e, Mlcd, MutLd, MutMb,c, NarPc,e, NrdHe, NusBc, PhoPc,e, PrlCb,c,e, PyrFc, RecAc, RecJc, RdgBc, RibEc, RluAb, RpmEe, RpoDd, RpsLe, RrmJd, rrnBd, SdaAc,e, ThiLc, TopAd, TreRe, TyrRc, ValSc, XerDc, YadFc,e, YafDc, YafEb,c, YbbNb,e, YbeDb,c,e, YbeYc, YbjXe, YccEe, YccVb,e, YcePb,c,e, YciHc, YcjXb,c,e, YdaMb, YdeOe, YdhQb,c,e, YeaDd, YfjNc, YfiAe, YgaDc, YgbFc, YggWc, YhdNc,e, YhiQb,c, YibAb,e, YjhIe, YjiTe, YnfKd, YrdAb,e, YrfHb,c, YrfGc,e, XapRe, ZntRc |
| Unknown (3) | yi81_1d, yi82_1d, YpjMe |
| Functional category | |
| Metabolism (22) | CutEc, FolPd, GapAd, IspHc, LdhAb,e, LipBc, LspAc, MenAd, NrdHe, PgpAc, PyrFc, RibEc, SdaAc,e, ThiLc, YadFc, YafEb,c, YceJc, YdaMb, YggWc, YibAb,e, YrdAb,e, YrfGc,e |
| Chaperone/folding catalysts (12) | ClpBd, DnaJd, DnaKd, DsbCc, FkpBc, GroELSd, GrpEd, Hsp33c, HtpGd, IbpAd, IbpBd, YbbNb,e |
| Protein degradation (11) | ClpPd, ClpXd, FtsHd, HflXd, HflKd, HflCd, HslUd, HslVd, HtpXd, Lond, PrlCb,c,e |
| DNA modification (9) | HolCc,e, Mfdb,e, MutLd, MutMb,c, RecAc, RecJc, RdgBc, TopAd, XerDc |
| RNA state (3) | Hfqd, RluAb, YfjNc |
| Transcription regulators (18) | CreBc, CreCc, CycAb, FimBe, HepAc,e, MacBb, Mlcd, NarPc,e, NusBc, PhoPc,e, PhoQc, RpoDd, TreRe, TyrRc, XapRe, YdeOe, YjhIe, ZntRc |
| Translation/tRNA (11) | GlnSc,e, IleSc,e, MiaAd, RpmEe, RpsLe, RrmJd, rrnBc, ValSc, YciHc, YfiAe, YrfHb,c |
| Transporter (7) | Crrc, GntXc,e, SdaCe, YbeXc, YbeZb,c,e, YdgRe, YehZe |
| Miscellaneous (6) | FxsAb,c,e, GntYc, YccVb,e, YhiQb,c, yi81_1d, yi82_1d |
| Unknown function (27) | CreAc, YafDc,e, YafUe, YbeDb,c,e, YbeYc, YbjXe, YccEe, YceIc,YcePb,c,e, YciMb,c, YciSb,c,e, YcjFb,c, YcjXb,c,e, YdhQb,c,e, YeaDd, YehRe, YgaDc, YgbFc, YgcIe, YghJe, YhdNc,e, YiaAe, YibGe, YjiTe, YnfKd, YpjMe, YtlLe |
a
The predicted functions (http://ecocyc.org) and locations (46) were obtained for all identified σ32 regulon products. Note that rrnB is an RNA. Underlined proteins are annotated as “membrane”; however, it is assumed that they are located in the inner membrane.
b
Identified in reference 67.
c
Identified in reference 43. Only regulon products encoded on the chromosome and with a confirmed σ32-dependent promoter are listed.
d
Previously known; referred to in reference 43.
e
Identified in reference 62.