FIG. 21.
Synthetic nonreacting analogs of the substrate (GlcNAc-Ins) for the MSH deacetylase MshB in which the NH residue is replaced by CH2 (G2) and the corresponding alcohol (G1); both G1 and G2 inhibit MSH biosynthesis in M. smegmatis, about twofold, at 200 μg/ml (33).