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Gene silencing of ATG7 by siRNA inhibits CVB3 replication. (A) Representative light microscopic images of CVB3-infected cells, with or without ATG7 siRNA transfection. (B) Western blot probing for VP1 and ATG7 expression, with or without ATG7 knockdown. VP1 expression was quantitated, normalized, and analyzed as described in the legend to Fig. 3 (data are means ± SE; n = 3). *, P < 0.05 compared to scramble siRNA-transfected cells.
