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Growth curve of FMDV type O1 variants in MCF-10A cells. Cells were infected with FMDV type O1Campos, O1C3056R, or O1C3056R-KGE at an MOI of 10 PFU/cell, as described in Materials and Methods. Combined intracellular and extracellular plaque titers were determined at different times p.i. in BHK-21 cells.
