FIG. 2.
Analysis of FMDV interaction with the αVβ6 integrin in MCF-10A cells. Cells were infected with type O1Campos (a to d), type O1C3056R-KGE (e to h), and type O1C3056R (i to l) or were mock infected (m) at 4°C as described in Materials and Methods. Cells were fixed and probed for viral proteins (red) and the αVβ6 integrin (green), as described in Materials and Methods, immediately p.a. (a, e, and i) or at various times after cells were shifted to 37°C (b to d, f to h, and j to l). Only the merged photomicrographs are shown.