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. Author manuscript; available in PMC: 2008 Dec 1.
Published in final edited form as: Nano Lett. 2007 Nov 13;7(12):3895–3900. doi: 10.1021/nl0724788

Figure 2. Schematic drawing of sequential surface modifications for streptavidin sensing.

Figure 2

(a) 50-nm-high nanochannel in Pyrex before surface modification. (b) Channel after coating with PLL-g-PEG/PEGbiotin, which monolayer has a height of ~12 nm.13, 14 (c) Final assembly after the streptavidin-biotin reaction, which binding can be sensed by a conductance change of the nanochannel.