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. Author manuscript; available in PMC: 2008 Dec 1.
Published in final edited form as: Nano Lett. 2007 Nov 13;7(12):3895–3900. doi: 10.1021/nl0724788

Figure 6.

Figure 6

Normalized conductance change as a function of buffer flow time at a velocity of ~3.1 mm/s (and 0 mm/s as control measurement). Before the experiment the nanochannels were coated with PLL-g-PEGbiotin and incubated in 10 µM streptavidin solution for 1 h. Applying high buffer flow velocities lead to a signal decrease and equilibrium after ~2 h, showing that the majority of the streptavidin-biotin interactions do not withstand high shear forces.