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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Bioconjug Chem. 2007 Dec 7;19(1):377–384. doi: 10.1021/bc700315v

Figure 4. Correlation between the degree of vehicle internalization and transfection efficiency.

Figure 4

(A) The degree of cellular internalization of various lipoplex and polyplex formulations incorporating NBD-oligos was determined based on the amount of unquenched NBD fluorescence following dithionite treatment, and was normalized by the total NBD fluorescence added to the cells. (B) Transfection efficiencies of identical formulations incorporating luciferase-encoding plasmid DNA are presented as mean RLU/mg protein ± standard deviation.