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. Author manuscript; available in PMC: 2008 Sep 22.
Published in final edited form as: Biochemistry. 2006 Mar 7;45(9):2836–2844. doi: 10.1021/bi051644s

Figure 5.

Figure 5

Illustrations of potential T4 DNA polymerase pre-insertion and closed complexes. Complexes II, III and IV correspond to the same complexes in Scheme 1. Structural data for pre-insertion complexes for T4 DNA polymerase or other DNA polymerases are not available; however the structures indicated for pre-insertion complexes II and III are consistent with the 2AP fluorescence data and complex II resembles the T7 RNA polymerase pre-insertion complex (21). Complex IV resembles closed complexes observed for several DNA polymerases.