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. Author manuscript; available in PMC: 2009 Jul 15.
Published in final edited form as: Cancer Res. 2008 Jul 15;68(14):5849–5858. doi: 10.1158/0008-5472.CAN-07-6130

Figure 1.

Figure 1

A) Western blot showing basal expression of TG2 protein in 11 ovarian cancer cell lines and one non-transformed normal ovarian epithelial cell line (HIO-180). B) Transglutaminase enzymatic activity according to TG2 expression levels. Mean enzymatic activity of TG2 was determined in the cell extract by studying Ca2+-dependent incorporation of [3H]putrescine into dimethylcasein, as described in Materials and methods. Error bars represent S.D. C) Representative immunohistochemical staining of clinical specimens for TG2 expression. All pictures were taken at original magnification × 200. D) Kaplan–Meier survival curve of patients with invasive ovarian cancer according to TG2 expression.