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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: J Proteome Res. 2007 Nov 23;7(1):328–338. doi: 10.1021/pr070300g

Figure 6.

Figure 6

Increase of mtDNA during neuronal differentiation. A. Total cellular DNA was prepared from undifferentiated cells and from cells at days 4 and 11 of the differentiation program. 10 μg samples of DNA were digested with EcoRI, fractionated by agarose gel electrophoresis, transferred to a Hybond N+ membrane and probed with a mixture of 32P-labeled probes to detect both nuclear rDNA and mtDNA. Hybridization of probes to DNA was detected and quantified with a phosphorimager. B. Quantification of mitochondrial DNA to nuclear ribosomal DNA.