Superimposition of lauric acid in hydrophobic channel of ecarpholin S and three Lys49-PLA2 enzymes. Structure of MjTX-II/stearic acid (Protein Data Bank code, 1XXS, red), PrTX-II/fatty acid (Protein Data Bank code, 1QLL, blue), ACL/lauric acid (Protein Data Bank code, 1S8G, yellow), and ecarpholin S/lauric acid (cyan) complexes were superimposed. Lauric acid molecules are shown as lines. Image was prepared using the program Pymol (59).