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. Author manuscript; available in PMC: 2008 Sep 23.
Published in final edited form as: J Agric Food Chem. 2006 Dec 27;54(26):9852–9857. doi: 10.1021/jf062808u

Figure 1. Affinity of black cohosh extracts to the human μ opiate receptor (hMOR) expressed in Chinese hamster ovary (CHO) cells.

Figure 1

Three black cohosh extracts, 100% methanol (CR-methanol), 75% ethanol (CR-ethanol), or 40% 2-propanol (CR-isopropanol), were used to displace the binding of [3H]DAMGO, a selective hMOR agonist, to CHO-hMOR cells. The affinities of these extracts, at three different concentrations (0.03, 0.1, and 0.3 mg/ml), were compared. The percentage inhibition of the specific radioactivity of [3H]DAMGO bound to the CHO-hMOR cell membranes was shown. Data are the mean ± SD (N = 3). * P < 0.05, ** P < 0.01, *** P < 0.001, compared with CR-ethanol; #P < 0.05, ** P < 0.01, comparison between CR-methanol and CR-isopropanol.