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. Author manuscript; available in PMC: 2008 Nov 14.
Published in final edited form as: J Am Chem Soc. 2007 Oct 20;129(45):14026–14033. doi: 10.1021/ja075247b

Figure 4.

Figure 4

Representative gel shift results for Exd in the presence of linear protein-DNA dimerizers with differently sized linkers on two distally-oriented DNA sites. (a) Schematic of the positions of the Exd and polyamide DNA-binding sites showing the A,T spacer region which was varied. (b) Gel shift experiments show that 1 forms a stable complex with Exd and DNA when there is a 2 bp overlap, i.e. a site spacing of −2, between the two sites, whereas 2 does not form a complex with Exd at any of these sites. Concentrations of the compounds and Exd are the same as described in Figure 3.