Figure 5.

Representative gel shift results for Exd in the presence of linear WMK tripeptide conjugates on select proximally-oriented DNA sites. (a) Schematic of the positions of the Exd and polyamide DNA-binding sites showing the A,T spacer region which was varied. (b) Gel shift experiments show that both 9 and 10 form stable complexes with Exd and DNA only when there is a 6 bp site spacing. Concentrations of the compounds and Exd are the same as described in Figure 3.