Table 2.
Dietary groups and HI subgroups |
Hippocampal subareaa |
||||
---|---|---|---|---|---|
CA1 | CA3ab | CA3c | Dentate gyrus | Parietal cortex | |
Iron-sufficient | |||||
15 min (n = 6) | 3.3 ± 4.2 | 0.0 ± 2.3 | 0.0 ± 2.3 | 0.3 ± 1.1 | 0.9 ± 0.2 |
30 min (n = 6) | 0.6 ± 6.2 | 0.0 ± 2.6 | 4.8 ± 5.4 | 0.0 ± 4.3 | 0.6 ± 0.2 |
45 min (n = 6) | 6.8 ± 7.1 | 0.0 ± 2.1 | 0.1 ± 3.0 | 1.0 ± 1.9 | 0.4 ± 0.3 |
Iron-deficientb | |||||
15 min (n = 6) | 3.7 ± 4.9 | 0.0 ± 1.2 | 0.0 ± 3.3 | 7.8 ± 4.6 | 0.2 ± 0.1 |
30 min (n = 9) | 18.8 ± 3.0c | 6.8 ± 6.9 | 2.5 ± 3.7 | 2.6 ± 2.3 | 0.3 ± 0.2 |
45 min (n = 8) | 17.6 ± 6.1 | 2.1 ± 3.9 | 0.0 ± 2.9 | 1.8 ± 2.3 | 2.8 ± 1.7 |
Values = mean ± s.e.m. % loss of Nissl staining intensity on the HI hemisphere when compared with the corresponding brain region on the control hemisphere.
Nomenclature based on Johansen (1993).
Main effect of iron-deficiency on Nissl staining intensity loss was seen for subarea CA1 (P = 0.03, univariate ANOVA).
Significantly different between iron-sufficient and iron-deficient groups (P < 0.01, Bonferroni-adjusted t-test).