A. Cytological borders of each medial surface photograph were co-registered to the Talairach and Tournoux (1988) coordinate system and corpus callosum as shown here for Case 2. Each of the borders were identified histologically (3 arrows) and measurements taken to the VCA as indicated with the double-headed arrows. B.-C. Activation sites in cingulate cortex were plotted in relation to the average coordinates for each border (dotted lines mark edge of cingulate cortex). The double arrow in B. suggests a point at which the density of sites associated mainly with short, noxious stimuli changes in the y axis. There is a striking localization of nociceptive activity in aMCC with a prominent aggregate around the VCA in pMCC. C. Most fear activity was in aMCC. D. Although Non-Emotion activity was striking in vPCC, none was in aMCC and pACC was virtually devoid of it. This suggests the latter activations are associated with processing specific to emotion. cgs, cingulate sulcus; g, b, s, genu, body, and splenium of the corpus callosum.