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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: Dev Biol. 2008 Jun 20;321(1):197–204. doi: 10.1016/j.ydbio.2008.06.017

Fig. 5.

Fig. 5

Pharmacologic inhibition shows PI3K activity is required for Pten but not Foxo3 ovarian phenotype. Ovaries were explanted at birth and cultured for 8 days. Solid lines, untreated; dashed bars, 25 μM LY294002. Squares = wild-type, triangles = Vasa-Cre; Pten−/L; circles = Vasa-Cre; Foxo3−/L. Graph on right shows oocyte diameters at the end of 8 day culture period. Ut = untreated, Ly = 25 μM LY294002. Note: The small apparent difference in untreated Pten−/L vs. Foxo3−/L oocytes is not significant (p = 0.40). Error bars = s. e. m.; p values calculated by Student’s T Test.