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. Author manuscript; available in PMC: 2009 Jul 24.
Published in final edited form as: Brain Res. 2008 May 14;1221:115–125. doi: 10.1016/j.brainres.2008.04.080

Table 1.

Within and between-group brain activation for letter and category fluency.

Location
(approximate Brodmann area)
Mean
Intensityd
Cluster
Volume
Talairach coordinates
x y z
Letter Fluency
    ASDa
L middle frontal G. (9) 0.26 6208 −41 15 25
    Controla
L middle frontal G. (9) 0.30 6016 −42 9 31
    ASD > Control b
R frontal (44) 0.39 7808 49 14 7
R inferior frontal G. (45) 48 25 7
R superior temporal G. (22) 54 7 4
    ASD > Control c
R frontal (44) 0.41 2176 50 11 4
R inferior frontal G. (45) 0.38 1024 46 24 11
Category Fluency
    ASDa
L insula 0.20 4992 −30 19 11
L inferior frontal G (9) 0.36 1920 −50 10 29
L medial frontal G. 0.36 1664 −4 1 52
    Controla
L middle frontal G. (46,9) 0.29 14272 −44 17 26
L inferior frontal G (45) −37 26 5
L medial frontal G. (32) 0.23 1792 −6 3 54
    Control > ASD b
L middle frontal G. (8) −0.5816 13760 −42 23 44
    ASD > Control c
R inferior frontal G. (47) 0.50 4672 52 19 −3
L inferior frontal G. (44) 0.33 2176 −55 3 17
L medial frontal G. 0.22 1600 −10 −15 51
    Control > ASD c
L middle frontal F. (8) −0.525 5248 −42 23 44
Category > Letter Fluency
    Controlb
Bilateral lingual gyrus (18) −0.4552 51648 −10 −87 −14
Bilateral cuneus (18) −2 −94 6
Bilateral medial frontal G. −0.4958 20928 −9 53 8
Left inferior frontal G. 36 −39 1
Left middle frontal G. 44 −47 4

Note. Talairach coordinates for other brain areas within the cluster are listed separately and italicized.

a

Voxel height p < .005, α = .05 (cluster volume corrected)

b

Voxel height p < .05, α = .05 (cluster volume corrected)

c

Results for ASD and controls groups matched on handedness. Voxel height p < .05, α = .05 ( uncorrected).

d

Intesity values correspond to the mean percent signal change between the task and control blocks.