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. 1985 Jul;55(1):45–53. doi: 10.1128/jvi.55.1.45-53.1985

DNA-binding proteins present in varicella-zoster virus-infected cells.

C R Roberts, A C Weir, J Hay, S E Straus, W T Ruyechan
PMCID: PMC254896  PMID: 2989559

Abstract

DNA-binding proteins present in varicella-zoster virus-infected cells were identified by DNA-cellulose chromatography of radioactively labeled cell extracts. Seven virus-specific proteins, ranging in molecular weight from approximately 175,000 to 21,000, showed affinity for single- or double-stranded DNA or both. These proteins include the varicella-zoster virus major capsid protein, a phosphorylated tegument protein, and a 125,000-molecular-weight species which may be analogous to the major DNA-binding protein of herpes simplex virus. We also identified a number of DNA-binding phosphoproteins by these procedures. Finally, protein blot studies were carried out to determine whether these proteins bind preferentially to virus rather than to host cell DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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