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Concise representation of homopolymers: formation and effects of p53 homotetramer. (1) The three additional copies of p53 monomer required to make up the tetramer are represented by three nodes placed side by side and linked to the identified p53 monomer; a node placed internally on this line represents the homotetramer itself. (2) p53 tetramer can bind to promoter element. (3) Tetramerization stimulates (or is required for) phosphorylation of p53 Ser15 by DNA-PK.
