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. 1999 Aug;10(8):2735–2743. doi: 10.1091/mbc.10.8.2735

Figure 2.

Figure 2

BoNT-C1, which specifically cleaves syntaxin, inhibits cell division in the sea urchin embryo. Injection of active BoNT-C1 blocks cells from dividing (5.3 nM; A–C), whereas uninjected cells or cells injected with either heat-inactivated BoNT-C1 (53 nM; G–I) or proteinase K (493 nM; G–I) develop normally. Cells injected with either BoNT-A (45 nM; J–L) or BoNT-E (58 nM; M–O), which specifically proteolyze SNAP-25, also divide as normal. Injected cells are marked with an oil droplet. Bar, 50 μm.