Table 6.
Gefitinib-related adverse events
| Skin | Diarrhea | ILD | |||
|---|---|---|---|---|---|
| Source (reference) | Grades 1-2/no. pts (%) | Grades 3-4/no. pts (%) | Grades 1-2/no. pts (%) | Grades 3-4/no. pts (%) | Grades 1-4/no. pts (%) |
| Inoue (43) | 12/16 (75%) | 0/16 (0%) | 3/16 (19%) | 0/16 (0%) | 0/16 (0%) |
| Asahina (44) | 7/16 (44%) | 1/16 (6%) | 7/16 (44%) | 0/16 (6%) | 1/16 (6%) |
| Sutani (45) | 9/27 (78%) | 1/27 (18.5%) | 5/27 (3.5%) | 0/27 | 0/27 (0%) |
| Yoshida (46) | 6/21 (28.5%) | 0/21 (0%) | 6/21 (28.5%) | 2/21 (9.5%) | 0/21 (0%) |
| Sunaga (47) | 13/21 (62%) | 1/21 (4.7%) | 2/21 (9.5%) | 0/21 (0%) | 1/21 (4.7%) |
| Total | 47/101 (46.5%) | 3/101 (3%) | 23/101 (23%) | 2/101 (2%) | 2/101 (2%) |
no. pts, number of patients; ILD, interstitial lung disease