Figure 6.
Effect of activation of calcium-sensing receptor on [Ca2+]i in the perimacular oscillatory cells. (A) Representative fura-2 ratio recording demonstrating the effect of neomycin, an activator of calcium-sensing receptor (5 × 10−4 mol/L from the bath), on [Ca2+]i in a perimacular cTAL cell located in the terminal portion of the cTAL. (B) Effect of neomycin on [Ca2+]i in perimacular tubular epithelial cells. ○, Fura-2 ratio values from individual cells; •, average values (n = 8, one cell each from every preparation; the values in the control and neomycin groups were different from each other; P < 0.05).