Table 5.
Results from variance components analysis of eGFR in HAPI Heart Study participantsa
Parameter | Physical Positionb | Coefficient | SE | Pc | nc |
---|---|---|---|---|---|
rs7918405 | 114,495,455 | −0.44 | 0.12 | 0.0003 (0.004) | 860 (466) |
rs7901695 | 114,744,078 | 0.18 | 0.09 | 0.0490 (0.013) | 858 (464) |
rs11196205 | 114,797,037 | 0.07 | 0.08 | 0.3920 (0.125) | 847 (454) |
rs1904444 | 115,067,346 | 0.38 | 0.12 | 0.0020 (0.009) | 839 (458) |
Results are adjusted for age, gender, BMI, SBP, waist circumference, and fasting glucose in a subset of participants. Results are presented for rs7901695 and rs11196205, which were also available in the ARIC Study, and for two of the other 64 SNP examined in the region.
Physical position based on NCBI Build 36.1 (March 2006).
P value/n for the entire sample, numbers in parentheses for the subsample with available fasting glucose measurements after further adjustment for fasting glucose.