Table 2.
For Dex-treated rats, 36 h of water deprivation resulted in an increase in urine volume and urinary urea excretion and a decrease in maximal urine osmolalitya
| Parameter | CTR | Dex | P |
|---|---|---|---|
| n | 7 | 7 | |
| % loss in body weight (%) | 6.3 ± 0.9 | 10.4 ± 1.1 | <0.001 |
| SOsm (mOsm/kgH2O) | 313 ± 3 | 314 ± 2 | NS |
| UVol before dehydration (μl/min per kg body wt) | 21 ± 2 | 35 ± 4 | <0.0001 |
| UVol after dehydration (μl/min per kg body wt) | 7 ± 1 | 11 ± 1 | <0.05 |
| UOsm after dehydration (mOsm/kgH2O) | 4017 ± 158 | 3580 ± 122 | <0.05 |
| UNaUVol (μmol/min per kg body wt) | 3.3 ± 0.2 | 2.9 ± 0.1 | NS |
| FENa (%) | 0.57 ± 0.06 | 0.48 ± 0.05 | NS |
| UUreaUVol (mg/min per kg body wt) | 0.24 ± 0.01 | 0.45 ± 0.03 | <0.0001 |
a
Data are means ± SEM.