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. 2008 Oct;19(10):1947–1954. doi: 10.1681/ASN.2008020174

Table 2.

Physiologic measurements before and during intravenous saline load

Parameter MAP (mmHg) HR (bpm) Hct (%) PNa (mEq/L) PK (mEq/L) GFR (μl/min per g)
α1R/Rα2R/R (n = 7)
    basal 82 ± 1 421 ± 28 51 ± 1 159 ± 1 4.3 ± 0.3 1259 ± 162
    saline 1 83 ± 2 452 ± 24 48 ± 1 158 ± 1 4.6 ± 0.3 1267 ± 183
    saline 2 86 ± 2 459 ± 20 47 ± 1 158 ± 2 4.8 ± 0.2 1315 ± 251
α1S/Sα2R/R (n = 8)
    basal 85 ± 2 385 ± 11 49 ± 0 156 ± 1 4.4 ± 0.2 1115 ± 79
    saline 1 88 ± 2 438 ± 13 48 ± 1 157 ± 1 4.7 ± 0.3 1179 ± 64
    saline 2 91 ± 3 446 ± 17 47 ± 1 155 ± 1 5.0 ± 0.3 1334 ± 83
α1R/Rα2S/S (n = 11)
    basal 81 ± 2 409 ± 11 51 ± 1 157 ± 1 4.8 ± 0.2 1337 ± 46
    saline 1 79 ± 2 441 ± 15 47 ± 1 157 ± 1 4.8 ± 0.2 1347 ± 117
    saline 2 81 ± 2 449 ± 14 45 ± 1 157 ± 1 5.0 ± 0.2 1357 ± 135
Two-way ANOVA
    group 0.011 0.670 0.510 0.440 0.730 0.700
    treatment 0.070 <0.001 <0.001 0.270 0.003 0.012
    group × treatment 0.433 0.370 0.180 0.470 0.590 0.190