Table 2.
Predictors for hospital mortality in patients with bacteremia due to E. coli or Klebsiella
| Variable | Hospital Non-survivors n = 71 (17%) |
Hospital Survivors n = 345 (83%) |
P-value |
| Age (mean in years, SD) | 59.6 ± 14.6 | 54.4 ± 16.3 | 0.01 |
| Male sex (n, %) | 29(40.9) | 159(46.2) | 0.41 |
| Polymicrobial bacteremia (n, %) | 22(31.0) | 67(19.4) | 0.03 |
| Appropriate empiric antimicrobial therapy (n, %) | 45(63.4) | 260(75.4) | 0.04 |
| Presence of central line at time of culture (n, %) | 48(67.6) | 177 (51.6) | 0.01 |
| APS before culture (mean, SD) | 34.9 ± 14.8 | 20.2 ± 13.8 | < 0.01 |
| Chronic disease score (mean, SD) | 7.9 ± 3.9 | 7.0 ± 3.9 | 0.08 |
| Time at risk (median in days, IQR)† | 8.0 (0.17 to 21.4) | 0.9 (0.1 to 8.8) | < 0.01 |
| Time to susceptibility (median in days, IQR)†† | 3.2 (2.8 to 4.1) | 3.0 (2.6 to 3.9) | 0.02 |
APS – modified acute physiology score
IQR – interquartile range
†Time at risk is the time from hospital admission to index culture collection
††Time to susceptibility is the time from index culture collection to the receipt of antibiotic susceptibility testing results
P-values were calculated using the Fisher's exact test or Chi-squared tests for categorical variables and the Student's t-test for continuous variables.