Table 2.
HRs for type 2 diabetes among 13,953 young adult men across quintiles of triglyceride levels
| Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | Ptrend | |
|---|---|---|---|---|---|---|
| Triglyceride (mg/dl) | 30–66 | 67–90 | 91–119 | 120–163 | 164–299 | |
| Person-years of follow-up | 15,941 | 15,115 | 15,340 | 15,428 | 15,100 | |
| No. incident cases of type 2 diabetes | 22 | 41 | 43 | 79 | 137 | <0.001 |
| Adjusted risk ratio (95% CI) | ||||||
| Age | 1 | 1.49 (0.94–2.35) | 1.72 (1.10–2.68) | 2.88 (1.90–4.36) | 4.77 (3.22–7.06) | <0.001 |
| Age and BMI | 1 | 1.21 (0.77–1.93) | 1.34 (0.86–2.08) | 1.89 (1.24–2.87) | 2.61 (1.75–3.91) | <0.001 |
| Age, BMI, and FPG | 1 | 1.16 (0.73–1.83) | 1.23 (0.79–1.92) | 1.69 (1.11–2.57) | 2.13 (1.42–3.19) | <0.001 |
| Age, BMI, FPG and family history of diabetes* | 1 | 1.18 (0.75–1.87) | 1.25 (0.80–1.95) | 1.72 (1.13–2.61) | 2.10 (1.40–3.14) | <0.001 |
| Multivariate† | 1 | 1.15 (0.73–1.82) | 1.24 (0.78–1.94) | 1.72 (1.12–2.64) | 2.11 (1.38–3.22) | <0.001 |
*
Family history of diabetes is a reported first-degree relative with type 2 diabetes
†
The multivariate Cox regression model was adjusted for age, BMI, total cholesterol–to–HDL cholesterol ratio, fasting plasma glucose, mean arterial blood pressure (continuous variables), family history of coronary heart disease (positive, negative, or missing information), physical activity (yes, no, or missing information), and smoking status (current smoker, noncurrent smoker, or missing information). To convert the values for triglycerides to millimoles per liter, multiply by 0.0113.