FIG. 6.

Pattern of c-Fos–positive cells and glucose utilization rates after an intragastric glucose infusion in high-fat diet–fed diabetic mice. The number of c-Fos–expressing cells was quantified in the NTS (A) and ARC, VMH, and DMN nuclei (B) of mice fed a high-fat, carbohydrate-free diet infused with water (□) or glucose (▪). Five mice per group were studied. Glucose flux (mg · kg⁻¹ · min⁻¹) was studied after 1 week (C) or 1 month (D) of high-fat, carbohydrate-free diet. TO, turnover; Glycol, glycolysis; and Gln Synth, glycogen synthesis. For all parameters, no difference was noted between groups.