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Diabetes increases Akt and tuberin phosphorylation and decreases OGG1 protein expression. A–C: Representative immunoblot shows an increase in phospho-Akt (p-Akt) (A) and phospho-tuberin (p-tuberin) (B) and a decrease in OGG1 expression (C) in homogenized kidney cortex of diabetic (D) compared with control (C) rats. GAPDH was used as a loading control.
