TABLE 2.
Genes changed in two models of obesity and type 2 diabetes
| Gene name | Gene symbol | Fold change |
|
|---|---|---|---|
| db/db | DIO | ||
| Neuronatin | Nnat | 9.4 | 2.5 |
| Leptin | Lep | 4.6 | 3.7 |
| Natriuretic peptide receptor 3 | Npr3 | 2.3 | 4.9 |
| Lectin, galactose binding, soluble 3 | Lgals3 | 2.2 | 3.5 |
| Transthyretin | Ttr | 4.0 | 0.4 |
| Apolipoprotein A-II | Apoa2 | 3.8 | 0.4 |
| Fatty acid binding protein 1 | Fabp1 | 3.4 | 0.4 |
| Cytochrome P450, family 3, subfamily a, 11 | Cyp3a11 | 3.1 | 0.4 |
| Group-specific component | Gc | 3.1 | 0.4 |
| Serine (or cysteine) peptidase inhibitor, clade A, 1c | Serpina1c | 2.8 | 0.2 |
Fold change represent values obtained after data analysis with Wilcoxon test. DIO, diet-induced obesity and diabetes. See supplemental research design and methods in the online appendix for the details of the data analysis.