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Sulfasalazine treatment increases inosine levels in sciatic nerve extracts of diabetic rats
| Rats | Inosine (nmol/mg protein) |
|---|---|
| Normal | 3.92 ± 0.47 |
| Diabetic | 3.98 ± 0.38 |
| Sulfasalazine-treated diabetic | 5.25 ± 0.64* |
Data are means ± SD of extracts from three to five animals analyzed by reverse-phase HPLC. Assays were performed 9 months after induction of experimental diabetes.
Significantly different from normal and diabetic rats at P < 0.05 (ANOVA, followed by Dunnett's test).
