FIG. 1.

Schematic representation of the UNC13B gene. The structure of UNC13B gene on chromosome 9 is presented with the respective positions of the 39 exons and of the 24 SNPs genotyped (rsID are given in Table 1), as well as the HapMap haplotype blocks (in D′). Arrows at both ends: SNPs selected through sequencing; single arrow: haplotype tagging SNPs selected from Hapmap; arrow with bullet: position of rs13293564, the SNP associated with nephropathy; dashed arrow with bullet: SNPs in complete association with rs13293564 (not typed).