Figure 1.

Primary structure of rat ANPK and sequence comparison. (A) Predicted amino acid sequence of ANPK (GenBank accession no. AF036959). The numbers on the left depict amino acid positions. The catalytic kinase domain and the AR interaction domain (AR ID) are boxed. (B) Sequence alignment of protein kinase domains of ANPK and Dyrk. Roman numerals on the top denote the conserved kinase subdomains according to Hanks and Quinn (1991). Invariant residues in all the protein kinases are depicted with asterisks below the residues.