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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Mol Pharmacol. 2008 Apr 18;74(1):203–212. doi: 10.1124/mol.108.044891

Figure 4. Concentration dependence of MTSEA-Biotin effects on α1H101Cβ2γ2 receptors.

Figure 4

Representative GABA (EC15) and GABA (EC15) + FLZM (EC95) current responses from a single oocyte expressing α1H101Cβ2γ2 receptors. Arrows indicate ten second exposures to a low concentration (50 μM) and then a high concentration (4 mM) of MTSEA-Biotin. FLZM potentiation of I-GABA is abolished following application of a low concentration of MTSEA-Biotin while I-GABA is unchanged. Application of a subsequent high concentration of MTSEA-Biotin increases I-GABA.