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Inhibition of the TPA-induced cell scattering in sMDCK-Rab5DN cells. wt MDCK (a), sMDCK-Rab5DN-10 (b), -Rab11DA-3 (c), or -Rab11DN-5 (d) cells were incubated in DMEM containing 10% FCS for 24 h. The cells were stimulated with 100 nM TPA. At 6 h after TPA stimulation, the cells were fixed, and analyzed by phase-contrast microscopy. The results shown are representative of three independent experiments. Bar, 50 μm.
