Table 10.

The frequency of variant amino acids in Helical Domain I of Vpr (Residues 17–33)

Residue	Residues in NL4-3 Vpr	Variant residue(s) noted in viruses of subtype B
17	E	A (3.3), D (0.4), G (0.4), Q (2.2), V (0.4)
18	W	no change
19	T	A (12.7), R (0.4)
20	L	I (4.4)
21	E	G (0.4)
22	L	F (0.4), I (1.1), P (0.4)
23	L	V (0.4), S (0.4)
24	E	G (0.4), K (0.4), Q (0.7), R (0.4)
25	E	A (0.4), D (2.9), K (0.4)
26	L	no change
27	K	N (0.4)
28	S	G (0.4), H (0.7), N (43.5), R (4.7), T (2.5)
29	E	D (0.4), V (0.4)
30	A	P (0.4)
31	V	A (0.4), D (0.4), I (0.4), L (0.4), T (0.4)
32	R	K (3.6), Q (0.4), W (0.4)
33	H	R (3.6)