Table 11.

The frequency of variant amino acids in the Interhelical Domain 1 of Vpr (Residues 34–37)

Residue	Residues in NL4-3 Vpr	Variant residue(s) noted in viruses of subtype B
34	F	no change
35	P	no change
36	R	G (1.1), W (1.8), S (1.5)
37	I	A (1.5), E (3.6), G (1.1), K (0.4), L (1.8), M (2.5), N (0.4), P (16), R (0.4), S (0.7), T (7.6), V (19.3)