Table 3.

The polymorphisms in Helical Domain I of Vpr (residues 17–33)

Residue	Residues in NL4-3 Vpr	Variant residue(s) noted in viruses of different clades	Number of variants
17	E	A, D, G, Q, T, V	6
18	W	G, R	2
19	T	A, I, L, M, P, R, S, V	8
20	L	I, M, V	3
21	E	A, D, G, K, T	5
22	L	F, I, M, P, T, V	6
23	L	S, V	2
24	E	D, G, K, Q, R	5
25	E	A, D, G, K	4
26	L	F, I	2
27	K	I, M, N, Q, R	5
28	S	A, D, E, G, H, I, K, N, Q, R, T, V	12
29	E	D, G, Q, V	4
30	A	D, P, S, T, V	5
31	V	A, D, I, L, M, T	6
32	R	G, K, Q, T, W,	5
33	H	R	1