Table 7.

The polymorphisms in Helical Domain III of Vpr (residues 54–77)

Residue	Residues in NL4-3 Vpr	Variant residue(s) noted in viruses of different clades	Number of variants
55	A	E, G, I, L, M, P, Q, R, S, T, V	11
56	G	E, R	2
57	V	A, L, M, W	4
58	E	A, G, I, K, L, M, Q, R, T, V	10
59	A	D, F, I, L, M, N, P, S, T, V	10
60	I	F, L, M, T, V, Y	6
61	I	A, L, M, T, V, Y	6
62	R	I, K, L, Q, S, T, W	7
63	I	F, L, M, S, T, V, Y	7
64	L	F, V	2
65	Q	H, R	2
66	Q	H, K, L, R	4
67	L	A, F, I, M, P, Q	6
68	L	I, M, P, R	4
69	F	L, S, V	3
70	I	A, T, V	3
71	H	L, Y	2
72	F	S, Y, L	3
73	R	G, S, T	3
74	I	F, H, L, M, N, S, T, V	8
75	G	K, R	2
76	C	G, S, Y	3
77	R	A, H, L, K, N, P, Q, S, T, W	10