Table 9.

The frequency of variant amino acids in the N-Terminus of Vpr (Residues 1–16)

Residue	Residues in NL4-3 Vpr	Variant residue(s) noted in viruses of subtype B*
1	M	no change
2	E	D (0.4)
3	Q	H (0.4), R (1.8)
4	A	D (0.7), T (0.4), V (1.1)
5	P	L (0.4), S (0.4)
6	E	A (1.1), D (0.4), K (1.1), Q (0.7)
7	D	N (6.2), V (0.4)
8	Q	H (1.1)
9	G	no change
10	P	L (0.4), S (0.7)
11	Q	A (0.7), E (0.4), P (1.8), S (1.8)
12	R	K (0.4)
13	E	I (0.4), Q (1.1), V (0.7)
14	P	Q (0.4), S (0.7)
15	Y	C (0.4), D (0.4), F (6.9), H (5.0), N (0.7), S (0.4), V (0.4)
16	N	A (0.4), H (1.1), I (0.4), Q (0.7), P (0.4), R (0.4), S (0.4), T (0.7)

*275 Vpr alleles were used for analysis.

The numbers in the parentheses represent the percent frequency of the variant amino acid in the Vpr alleles analyzed.