Table 3.

Top SNPs ranked by univariate analysis for trial S9321

Rank	rs ID	pval	Gene Sym	Gene Name	SNP Function
1.0	rs2066534	0.001280	FMO3	Flavin containing monooxygenase 3	intron
2.0	rs696217	0.001877	GHRL	Ghrelin precursor	coding-nonsynon
3.0	rs1043424	0.002404	PINK1	PTEN induced putative Kinase 1	coding-nonsynon
4.0	rs174680	0.003361	COMT	Catechol-O-methyltransferase	intron
5.0	rs316132	0.003443	GSTA4	Glutathione S-transferase A4	intron, TagSNP:GSTA4
6.0	rs1884725	0.004564	XDH	Xanthine dehydrogenase	coding-nonsynon
7.0	rs2069391	0.004830	CDK2	Cyclin-dependent kinase 2
8.0	rs4148217	0.006167	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)	coding-nonsynon
9.0	rs11700112	0.007423	PAK7	P21 (CDKN1A)-activated kinase 7	coding-nonsynon
10.0	rs1052536	0.007643	LIG3	Ligase III, DNA, ATP-dependent	untranslated
11.0	rs2618346	0.008033	DUSP1	Dual specificity phosphatase 1	3' UTR
12.0	rs9282564	0.008239	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1	coding-nonsynon
13.0	rs53683	0.008429	GHRL	Ghrelin precursor	intron
14.0	rs2227314	0.009244	IL12A	Interleukin 12A (natural killer cell stimulatory factor 1, cytotixic lymphocyte maturation factor 1, p35)	intron
15.0	rs1801243	0.010739	ATP7B	ATPase, Cu++ transporting, beta polypeptide (Wilson disease)	coding-nonsynon
16.0	rs2953983	0.010792	POLB	Polymerase (DNA directed), beta	intron
17.0	rs4148946	0.011822	CHST3	Sarbohydrate (chondroitin 6) sulfotransferase 3	untranslated
18.0	rs7185307	0.011895	TNFRSF17	Tumor necrosis factor receptor superfamily, member 17	locus, TagSNP:TNFRSG17(BCMA)
19.0	rs699473	0.012077	SOD3	Superoxide dismutase 2, extracellular	intron
20.0	rs880324	0.012969	NFATC2	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	intron