Table 1.
Clinical summary
| Individual | Gender | First symptoms | Disease duration | APOE genotype | Clinical presentation | |||
| (years) | (years) | Psychosis | FTD | ALS | Dementia* | |||
| II-2 | M | ~45 | ~18 | - | + | - | - | |
| III-3 | M | ~59 | ~7 | e3/e4 | - | + # | - | - |
| III-5 | F | ~45 | ~11 | - | + | - | - | |
| III-7 | F | ~59 | 2 (alive) | e3/e4 | - | + | - | - |
| IV-1 | F | 43 | 3 (alive) | e3/e4 | - | + | - | - |
| II-5 | F | 63 | 1 | - | + | + | - | |
| III-6 | M | 58 | 3 (alive) | e4/e4 | + | + | + | - |
| III-8 | F | 46 | 4 | e2/e4 | + | - | + | - |
| III-12 | M | 46 | 5 | e4/e4 | - | - | + # | - |
| III-2 | F | 68 | 7 | e3/e4 | - | - | - | + # |
| II-7 | F | 50 | 16 | - | - | - | + | |
* Refer to the text for details.
# Diagnosis confirmed by neuropathological examination