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Electron micrographs showing sections of wild-type PC12 (WT) and trk-PC12 (Trk+) cells. Although LDCGs (identified by their dense content; arrowheads) are abundant in wild-type PC12 cells, they are absent in trk-PC12 cells. On the contrary, clathrin-coated vesicles, as well as all other cellular organelles, can be observed in both cell types. Bar, 500 nm.
