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. 2008 May 30;95(8):3840–3849. doi: 10.1529/biophysj.107.128322

FIGURE 9.

FIGURE 9

Artist view illustrating the “wedge-repulsion” model: SF molecules penetrate into the hydrophobic core of membranes because of favorable hydrophobic forces, and an electrostatic repulsion occurs between negative charges of peptidic amino acids Glu/Asp and negatively charged lipid headgroups. This promotes an increase in local membrane curvature, which destabilizes MLV (A) to form SUVs (B).