TABLE 2.
Comparison of bidomain to AsymDM AP waveshapes
| fe | Model | Extra bias | θ (cm/s) | (φm)max (mV) | (∂φm/∂t)max (mV/ms) | τfoot (μs) | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 | Bidomain | 56.8 | 22 | 246 | 218 | ||||||
| 0.25 | Symmetric DM | 1:1 |  |
 |
 |
 |
|||||
| 0.25 | Asymmetric DM | 1:10 |  |
 |
+2% | −1% | +1% | ||||
| 1:50 | −2% | −2% | +10% | −3% | +5% | ||||||
| 1:250 | −4% | +1% | −4% | +34% | −14% | +18% | |||||
| 1:500 | −4% | +19% | −3% | +40% | −20% | +25% | |||||
| 1:1000 | −1% | +36% | +1% | +31% | −25% | +27 | +29% | ||||
| 0.10 | Bidomain | 49.4 | 22 | 244 | 217 | ||||||
| 0.10 | SymDM | 1:1 |  |
 |
 |
 |
|||||
| 0.10 | AsymDM 1 | 1:10 | −1% | −1% | +5% | −2% | +2% | ||||
| AsymDM 2 | 1:50 | −3% | −2% | −4% | +21% | −8% | +10% | ||||
| AsymDM 3 | 1:250 | −3% | +25% | −1% | +37% | −22% | +26% | ||||
| AsymDM 4 | 1:500 | +1% | +41% | +1% | +18% | −24% | +28% | ||||
Table shows the percent change in AP characteristics from AsymDM models with a nonuniform distribution of extracellular space compared to the equivalent bidomain representation (
). The two percentages correspond to divergent values of the confined membrane and the nonconfined membrane (bold values). If only one percentage is given, the measured values for the pair were nearly equivalent.